Homophobic and transphobic bullying in schools can have a serious effect on children and young people subjected to it at a crucial moment in their lives. It is an obstacle to the right to education, which is one of the basic universal human rights enshrined in the Universal Declaration of Human Rights and various United Nations Conventions. This article examines the global prevalence of homophobic and transphobic bullying in educational institutions; programmatic interventions by United Nations agencies to prevent and address it; and how international human rights frameworks such as the Convention on the Rights of the Child can be used to protect the rights of lesbian, gay, bisexual, and transgender (LGBT) children and young people in and through education.