College or university presidents (or chancellors, depending on the institution) get paid the big bucks to worry about the big picture: capital campaigns, attracting and retaining students, creating and sustaining quality academic programs, shared governance. It's a demanding job even when everything goes well, but when problems arise, challenges can turn into controversies that make the job a lot less rewarding. The vast majority of higher education leaders meet their challenges with energy and enthusiasm. However, stress and controversy are an inescapable part of the job, and for women or minority presidents, the inevitable skirmishes can take on a whole new dimension. Are there challenges unique to women presidents? And are those challenges multiplied when those women also happen to be minorities? In this article, six minority women presidents were asked to answer these questions. They are: (1) Dr. Ding-Jo Hsia Currie, Coastline Community College; (2) Dr. Juliet Garcia, University of Texas at Brownsville; (3) Zerrie Campbell, Malcolm X College; (4) Dr. Karen Gayton Swisher, Haskell Indian Nations University; (5) Dr. Patricia Granados, Triton College; and (6) Dr. Beverly Daniel Tatum, Spelman College. While they have much in common, these women also bring unique experiences and skills to a very demanding and often lonely job.