Confirmatory factor analytic procedures are routinely implemented to provide evidence of measurement invariance. Current lines of research focus on the accuracy of common analytic steps used in confirmatory factor analysis for invariance testing. However, the few studies that have examined this procedure have done so with perfectly or near perfectly fitting models. In the present study, the authors examined procedures for detecting simulated test structure differences across groups under model misspecification conditions. In particular, they manipulated sample size, number of factors, number of indicators per factor, percentage of a lack of invariance, and model misspecification. Model misspecification was introduced at the factor loading level. They evaluated three criteria for detection of invariance, including the chi-square difference test, the difference in comparative fit index values, and the combination of the two. Results indicate that misspecification was associated with elevated Type I error rates in measurement invariance testing. (Contains 8 tables, 3 footnotes, and 3 figures.)