A growing body of literature demonstrates the co-occurrence of posttraumatic stress disorder and substance use disorder for females seeking substance abuse treatment. Nonetheless, relatively few trauma-specific treatments have been implemented or evaluated with this population. In this quasi-experimental study (N = 170), the Trauma Recovery and Empowerment Model (TREM) was modified for use in an existing residential substance abuse program. Women who participated in the TREM showed significantly better outcomes than those who received treatment-as-usual on trauma-related symptoms, although not on alcohol or drug use. TREM appears to be a promising model that can be embedded in a residential substance abuse treatment setting. Implications for practice and further research are discussed. (Contains 4 tables.)