The present study investigated the role of neuroticism and perceived school-related stress in somatic symptoms among a sample of 327 (167 females and 160 males) students in two Norwegian junior high schools. The results suggest that the role of neuroticism on somatic symptoms may be overestimated, and that the role of stress may be underestimated if neuroticism, stress and somatic symptoms are measured at the same time. In this study, both neuroticism and perceived school-related stress were found to be significantly associated with somatic symptoms.