This booklet, one of a series of 17 developed at Prince George's Community College, Largo, Maryland, provides an individualized, self-paced undergraduate organic chemistry instruction module designed to augment any course in organic chemistry but particularly those taught using the text "Organic Chemistry" by Morrison and Boyd. The entire series of modules covers the first 13 chapters of the Morrison-Boyd text in great detail. Each module has been provided with from one to three audiotapes, available from Prince George's Community College, to provide students additional explanations of particular concepts. Each module includes a self-evaluation exercise, a reference guide, worksheets to be completed with the audiotapes, answer sheets for the worksheets, a progress evaluation, an answer sheet for the progress evaluation, an answer sheet for the self-evaluation exercise, an introduction to the topic covered by the module, and student performance objectives for the module. The topic of this module is the history of optical activity and enantiomerism. (SL)