The purpose of this study is to find out whether university students' attitudes towards physics lesson, their self-efficacy beliefs and burnout levels predict their academic success in physics lessons. The research group consists of 641 university students of which 307 are girls (47.1%) and 334 boys (52.9%). The research data were collected using "Physics Attitude Scale" developed by Ozyurek and Eryilmaz, "Physics Self-Efficacy Scale" developed by Caliskan et al., "Maslach Burnout Inventory-Student Survey" developed by Schaufeli et al., which was adapted to Turkish by Capri et al. and "Personal Information Form" developed by the researcher. "Multiple Regression Analysis" and "Stepwise Regression Analysis" were used for the analysis of the data. The analysis indicated statistically significant findings that predicted the academic success in physics lessons of the university students. The findings are discussed in accordance with the literature.