Librarians throughout higher education must assess information literacy; however, many are overwhelmed by the prospect of selecting the best assessment for their campus context. This article presents six questions to aid librarians in surmounting this challenge. Are we ready to conduct an information literacy assessment? Why are we conducting this assessment? What are the stakeholder needs? Will the assessment tell us what we want to know? What are the costs of this assessment? What are the institutional implications of this assessment? Armed with the answers to these questions, librarians will be well positioned to make informed assessment choices. (Contains 2 figures and 56 notes.)