Peer reviewed
Direct linkERIC Number: EJ749841
Record Type: Journal
Publication Date: 2006-Jan-1
Pages: 0
Abstractor: Author
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Diastereoselectivity In The Reduction Of Alpha-Hydroxyketones: An Experiment For The Chemistry Major Organic Laboratory
Ball, David B.
Journal of Chemical Education, v83 n1 p101 Jan 2006
An experiment is developed that requires the use of the NMR spectrometer via a NOESY1D experiment to determine the diastereoselectivity in the reduction of alpha-methylbenzoin with various reducing agents. Students must synthesize racemic alpha-hydroxyketones, perform reductions under chelating and non-chelating conditions, and quantitatively determine the relative amounts of diastereomic diols produced.
Descriptors: Organic Chemistry, Laboratory Experiments, Science Experiments, Higher Education, Science Education
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail: jchemed@egpp.com; Web site: http://jchemed.chem.wisc.edu/
Publication Type: Journal Articles
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
