Responsibility for support of technology in teaching and learning at the University of Missouri-St. Louis (UMSL) falls within the Information Technology Services (ITS) unit. Notwithstanding funding challenges, the university has been systematically renovating classrooms to meet the demands of increasing campus use of technology in teaching. Upgrades have included desks and chairs, as well as technological aids such as data projectors, instructor computers, and personal classroom responders ("clickers"). The growing body of recent literature on new classroom design encouraged UMSL to begin planning for a different kind of classroom. In this article, the authors describe the planning, creation, use, and initial assessment of the university's first Learning Studio--a space that had to be immediately useful, but also unabashedly provocative and experimental. The learning studio is an important harbinger of change on the UMSL campus, both in the conceptions of teaching and learning and in the approach to development of physical space. (Contains 9 figures, 2 tables and 32 endnotes.)