In this paper, the author's first and foremost objective is to render the answer to the following question: Why is spirituality marginalized in the academy? The author searches for the answer to this question in the terrain of knowledge production and worldviews that permeate the Western academy. The author examines the landscape of the neo-colonial academy and delineates the conditions that restrict the spaces for spirituality. The author's second objective is to explore possible answers to the following question: How would centering spirituality transform our ways of knowing? The author attempts to answer this question by providing some preliminary ideas on the question of epistemology, methodology and methods in a spiritually based inquiry. The author concludes that this journey is endless and this paper is just a stepping stone to the discussion revolving around the integration and centering of spirituality within the academy.