This laboratory manual presents activities for a unit of science within the Biomedical Interdisciplinary Curriculum Project (BICP), a two-year interdisciplinary precollege curriculum aimed at preparing high school students for entry into college and vocational programs leading to a career in the health field. These twenty-five laboratory activities concentrate on biomedical problems in investigating various aspects of the circulatory system, providing concrete experiences for students to explore the heart and blood vessels, blood and its properties, and the urinary tract. (CS)