This guidebook resulted from a student mentoring and teacher ambassador project in applied science in Wyoming. For the teacher-ambassador component of the program, seven science and vocational teachers interned in science-related industries to investigate technical-level jobs at 11 business and industry sites. They documented skills needed by workers in those jobs, looking at science and other core of knowledge skills such as communications, mathematics, biology and chemistry, and technology. This guidebook used by the teachers in the project lists the businesses investigated, the contact person at each site, a description of the worksite, the basic skills used on the jobs, the technical skills used in the jobs, and suggested applications to the classroom and the school district. Questions to be answered by students on field trips to the companies are also included. (KC)