This paper describes DO-IT (Disabilities, Opportunities, Internetworking and Technology), a cooperative program of the University of Washington and the High School/High Tech program to increase the career success of individuals with disabilities by providing access to technology, career preparation activities, and work experiences. DO-IT works with high school teachers, post-secondary faculty, and employers and helps people with disabilities to use computers, adaptive technology and the Internet; to transition from high school to college or from two-year to four-year colleges; and to transition from school to work. DO-IT activities include: Internet, college transition and career preparation; a summer study and summer camp programs for youth with disabilities; Internet-based mentor support, peer support through on-line communities of students with disabilities; leadership opportunities for students; and internships, cooperative education and other work-based learning experiences. High School/High Tech focuses on creating partnerships among state and local stakeholders to promote careers in science, engineering, and technology for students with disabilities. Among its activities are site visits by students to high tech businesses, mentoring, job shadowing, and summer and part-time employment. (DB)