There is a growing public awareness and evidence that now a postsecondary education leads to a higher degree of economic, civic, and social participation in society. There also is a growing realization that earning a two- or four-year degree is imperative to basic job preparation. In spite of this growing consciousness, those who desire a college education often face what they perceive as insurmountable barriers. To eliminate these barriers that derail students' college aspirations, American higher education must provide a wide array of access alternatives by making multiple entry points available to students throughout their lifetimes and changing occupational requirements. Recognizing that access and persistence issues vary according to region, the solutions colleges and universities seek need to be tailored to their own campuses. One-size-fits-all responses are not the answer to removing these obstacles. However, findings from recent research and results from successful campus-based programs and initiatives may provide a starting point. In this article, the author considers some actions that presidents--regardless of institution type or location--can take. He suggests that colleges and universities push the access agenda in public policy discussions with state and federal officials and make it a priority on their campuses. Concurrently, their campuses must assess policies and practices, and revise them so that students have better opportunities to enroll, graduate, and help shape the nation's future. (Contains 2 notes.)