Every step in a student's life is important for future success. Schools are building stronger frameworks of curricula, instruction and assessments to prepare students to move from one learning environment to another with maximum results as they journey toward adulthood. This issue of "High Schools That Work" contains examples of "best practices" implemented at the following schools: (1) Peter Alba Middle School (AMS) in Bayou La Batre, Alabama; (2) Rosemore Middle School (RMS) in Whitehall, Ohio; (3) Theodore High School (THS) in the Mobile suburb of Theodore, Alabama; (4) Jefferson County Public Schools system in Louisville, Kentucky; (5) Arkadelphia College Preparatory Academy (ACPA) in Clark County, Arkansas; (6) Logan County High School (LCHS) in Russellville, Kentucky; (7) Eastview High School (EVHS) in Apple Valley, Minnesota; (8) East Community Learning Center (ECLC) in Akron, Ohio; (9) Mary G. Montgomery High School (MGMHS) in Semmes, Alabama; (10) Apopka High School in Apopka, Florida; (11) Theodore High School (THS) in Theodore, Alabama; (12) The Leadership Program (TLP) in New York City; (13) Champlain Valley Educational Services, CV-TEC Division, in Plattsburgh, New York; (14) Willow Springs High School (WSHS) in Willow Springs, Missouri; (15) Indian Land High School in Fort Mill, South Carolina; and (16) Middle Tennessee State University (MTSU) in Murfreesboro, Tennessee.