The primary goal of this study was to evaluate the relative effectiveness of a skills-focused preschool curriculum versus a curriculum designed to foster children's self-regulation skills. Additionally, the study was designed to evaluate if adding a self-regulation component to a skills-based curriculum would enhance children's outcomes in academic skills, self-regulation skills, or both. Through manipulation of curricula used by classrooms, the study tested the value of providing preschool children at risk of academic difficulties with explicit practice in self-regulation skills over and above the impacts of language and literacy interventions on their own. (Contains 2 tables.)