We present a conceptualization and a 2 year program of autonomy-supportive I-Thou dialogue among teachers and students that is based on self-determination theory (Deci and Ryan in "Psychol Inq" 11(4):227-268, 2000) and Buber's (1960) philosophy. The program was applied in 18 seventh grade classes (420 students). Findings showed: (a) increases in positive emotions and in perceptions of teachers as conducting more dialogue on the relevance of studies to students' lives, and (b) decreases in negative emotions and in classroom violence. The findings highlight the importance of autonomy-supportive I-Thou dialogue and suggest that such dialogue might help adolescents to experience studying and school as more pleasant and secure.