Educators have successfully used various forms of entertainment media to inform the public about a wide range of subjects. Some of these methods have been implemented as learning tools for use in an academic setting. This study explores the attitudes of a student population using print education-entertainment as a supplement to classroom learning. In this participatory study, biology students reviewed a custom cell biology graphic novel (comic book) before studying the subject in an enrolled course, and provided feedback on how they felt about using it as a complementary learning aid in a Q-Methodology survey. The cell biology graphic novel was designed and written by the primary investigator using similar structure and informational content found in multiple high-school and college-level textbooks. Q-sample statements were then developed by the primary investigator. These statements were sorted (Q-sort) by participants according to which statements they agreed or disagreed with most. The results of this Q-Method study have outlined five different attitude profiles within the tested population, each indicating which aspects of this education-entertainment were most important to the students while learning basic cell biology. (Contains 1 figure and 6 tables.)