As I look back at K-12 science education in post-World War II America, it strikes me that surprisingly little progress has been made. This disappointing outcome cannot be due to a lack of effort, for in the last half-century our investment in science education reform--human and financial--has been substantial. In this essay, I focus first on some of our failures (as I see them) of the last 50 years, and speculate on why we were not more successful. With that in mind, I then propose a reform agenda for the next 50 years.