In this essay I explore a number of questions about purposes and methods in science education research prompted by my reading of Wesley Pitts' ethnographic study of interactions among four students and their teacher in a chemistry classroom in the Bronx, New York City. I commence three "lines of flight" (small acts of Deleuzo-Guattarian deterritorialization) that depart from the conceptual territory regulated by science education's dominant systems of signification and make new connections within and beyond that territory. I offer neither a comprehensive review nor a thorough critique of Wesley's paper but, rather, suggest some alternative directions for science education research in the genre he exemplifies.