In this article, Gene Fellner reviews Mark Zuss's recently published "The practice of theoretical curiosity" (2012) and provides a synopsis of the book's structure. These two sections are followed by a metalogue in which Mark Zuss, Welsey Pitts, and Fellner discuss curiosity and the conundrum of establishing limits beyond which curiosity should not roam. This is a central theme of Zuss's book, and it is of particular significance today as curiosity, driven by developments in technoscience and transgenics, transforms nature and we who are part of it. Influenced by Merleau-Ponty's phenomenological lens, Zuss discusses how our knowing the world through our senses is entering an uncertain future mediated by curiosity's reach into everyday life.