There is no published empirically based research on the new GCE synoptic assessment. Consequently no published research has been undertaken on its role, how it is taught or how pupils are prepared for the assessment. Neither is there a published evaluation of the effectiveness of teaching the synoptic units. It is these issues which are addressed in the present study. One hundred and twenty-five chemistry teachers replied to a questionnaire about the teaching strategies that they used and how they prepared candidates for A2 assessments. The analysis of the questionnaire responses found that it is the type of assessment--coursework or examination--that closely corresponded with the teaching strategies, perceived learning outcomes and approaches to preparing pupils for A2 assessments. The questionnaire responses were merged with GCSE and A level results. A series of multilevel models were fitted to identify any relationship between relative progress from mean GCSE scores to A level unit results and the questionnaire responses. Only significant results are presented and discussed. The synoptic unit and another A2 unit were assessed by a traditional written examination. Teaching the latter unit separately to other units and teachers' question spotting related to lower relative progress from mean GCSE to A level examination results. For the synoptic unit, teachers' question spotting related to a lower relative progress from mean GCSE to unit marks. For this unit the following related to higher relative progress from mean GCSE to synoptic unit results: (i) the teachers using grade descriptors to inform their preparation of pupils for the assessment; (ii) including the whole of the AS curriculum in revision sessions. For the coursework, the following related to higher relative progress from mean GCSE to unit marks: (i) pupils doing worked examples or exercises; (ii) teachers using statistical information about examination performance prepared by an external organisation for their centre. The following are appended: (1) The role of the synoptic unit in chemistry; and (2) Questions and responses to the chemistry questionnaire given as means (or % Yes) and frequencies. (Contains 8 tables and 5 notes.)