In Islam, knowledge, its acquisition and application is a fundamental requirement for all Muslims to enable them to believe, think, and act according to the principles of the religion. However, differences in style of interpretation of the Qur'an have led to text being interpreted against its own fundamental worldview; an example is the recent attempted assassination of a Pakistani girl for advocating female education. Based on analysis of selected verses, this article argues that the worldview of the Qur'an places importance on gaining knowledge of different kinds to fulfill divine requirements as well as all forms of human endeavor.