The development of a knowledge-based economy relies greatly on developing the skills and education needed for inclusive and sustainable development so that growth will reach all parts of the society. Addressing skills development for all is challenging for all OECD countries; Asian economies are working towards developing integrated pathways of skills and employment. This paper addresses some key aspects of skills development in OECD countries through a case study of small and medium enterprises as a key sector in both OECD and Asian economies. It extracts some lessons from this analysis that apply to the unique nature of skills development in Asia.