RNA modification, RNA interference, and RNA repair are important events in the cell. This thesis presents three projects related to these three fields. By using both biochemical and structural methods, we characterized enzymatic activities of pseudouridine synthase TruD, solved the structure of "A. aeolicus" GidA, and reconstituted a novel…

This dissertation examines the effect of Coulomb interactions in Hanbury Brown-Twiss (HBT) type experiments with electrons. HBT experiments deal with intensity interference, which is related to the second-order correlation function of the particle field. This is an extension of the usual amplitude interference experiment, such as Young's…

This dissertation considers whether or not archaeology was an effective tool for nation-building elites in Republican China (1912-1949), by looking at the discipline's fortunes in the off-center locale of Sichuan province. Through consideration of the multiplicity of agents and motives involved in archaeological enterprise in Republican Sichuan,…

To understand the issues of inquiry-based education, I adopted John Dewey's theory of inquiry as the analytical framework to examine science learning activities, students' interactions, and education standards. Educators have tried to engage students in meaningful learning, but the analysis revealed that the meaning of inquiry was diverse:…

The purpose of this study was to find out if students were utilizing Web 2.0 applications. Since the applications in question are often employed by the media industry, the study aspired to find out if students majoring in mass communication and journalism utilized the applications more often than other students. The "digital divide" is a term used…

This dissertation explores the milieu in which children of Imperial Berlin were raised. When contemporaries in the rapidly expanding capital of the Second German Empire (1871-1918) looked at children, this milieu darkened. The city, they argued, threatened children's growing bodies, and such institutions as the home, the clinic, and the school…

This qualitative study elicited key themes in an attempt to understand the nature and essence of the career advancement experiences of a select group of African American male community college presidents. Research was conducted through a "culturally sensitive" research design (Tillman, 2002) that contained four elements: "culturally congruent…

The Depression and the New Deal brought together a variety of conditions and social forces that set up a formative clash over the institution of professional journalism. At the heart of that fight was the rise of the American Newspaper Guild and its battle for control over the trusteeship of the freedom of the press. The experience in the news…

This study modeled changes in pre-service teacher efficacy in mathematics and science over the course of the final year of teacher preparation using latent transition analysis (LTA), a longitudinal form of analysis that builds on two modeling traditions (latent class analysis (LCA) and auto-regressive modeling). Data were collected using the…

Measurements of social constructs that evaluate natural hazard preparedness are important to decrease natural hazard vulnerability. Preparedness reduces natural hazard impacts and human vulnerability. Investment in education and education research contribute to human sustainable development and natural hazard preparedness. Faced with other needs,…

The focus of this research is an examination of service quality provided by non-centralized technology personnel, Local Technical Support Providers (LSPs), at a southern research university. The SERVQUAL instrument was selected to measure service quality of LSPs within the Academic Affairs Division. The rationale for selecting and testing SERVQUAL…

Doctoral studies are at the apex of the education system. Attracting, recruiting, enrolling, and graduating the best suited students in doctoral education is, therefore, critical in ensuring the highest academic standards and service to society. Focusing on Rowan University's Doctor of Education (Ed.D.) in Educational Leadership program, this…

This research targeted the area of Ontology-Driven Information Systems, where ontology plays a central role both at development time and at run time of Information Systems (IS). In particular, the research focused on the process of building domain ontologies for IS modeling. The motivation behind the research was the fact that researchers have…

In today's world, information is increasingly created, processed, transmitted, and stored digitally. While the digital nature of information has brought enormous benefits, it has also created new vulnerabilities and attacks against data. Unlike physical documents, digitally stored information can be rapidly copied, erased, or modified. The…

Group decision making is essential in organizations. Group Support Systems (GSS) can aide groups in making decisions by providing tools and process support. GSS is especially useful for geographically or temporally distributed groups. Researchers of GSS have pointed out that convergence processes are hard to accomplish in GSS. Voting tools in GSS…