The purpose of this qualitative study was to explore the literacy difficulties experienced by people with physical disabilities, and the factors that prevent them from improving their literacy skills. Semistructured interviews were conducted with 25 individuals with physical disabilities who defined themselves as having literacy difficulties. Four common themes emerged from the data analysis: (a) a wide range of mostly negative emotional responses, (b) numerous difficulties experienced at school, (c) troubling attitudes and expectations of others, and (d) a continued motivation to improve literacy skills. Implications for practitioners include more training to address the needs of physically disabled learners. This may mean experimenting with technical devices that facilitate learning, and consulting with occupational therapists. (Contains 3 tables.)