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Showing 1 to 15 of 285 results
Peer reviewed
Direct linkLiu, Jie; Chaplin, Tara M.; Wang, Fei; Sinha, Rajita; Mayes, Linda C.; Blumberg, Hilary P. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Adolescence is a critical period in the development of lifelong patterns of responding to stress. Understanding underpinnings of variations in stress reactivity in adolescents is important, as adolescents with altered stress reactivity are vulnerable to negative risk-taking behaviors including substance use, and have increased lifelong…
Descriptors: Stimuli, Infants, Psychopathology, Adolescents
Arnsten, Amy F. T.; Rubia, Katya – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: This article aims to review basic and clinical studies outlining the roles of prefrontal cortical (PFC) networks in the behavior and cognitive functions that are compromised in childhood neurodevelopmental disorders and how these map into the neuroimaging evidence of circuit abnormalities in these disorders. Method: Studies of animals,…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Anxiety Disorders, Brain Hemisphere Functions
McMakin, Dana L.; Olino, Thomas M.; Porta, Giovanna; Dietz, Laura J.; Emslie, Graham; Clarke, Gregory; Wagner, Karen Dineen; Asarnow, Joan R.; Ryan, Neal D.; Birmaher, Boris; Shamseddeen, Wael; Mayes, Taryn; Kennard, Betsy; Spirito, Anthony; Keller, Martin; Lynch, Frances L.; Dickerson, John F.; Brent, David A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To identify symptom dimensions of depression that predict recovery among selective serotonin reuptake inhibitor (SSRI) treatment-resistant adolescents undergoing second-step treatment. Method: The Treatment of Resistant Depression in Adolescents (TORDIA) trial included 334 SSRI treatment-resistant youth randomized to a medication…
Descriptors: Outcomes of Treatment, Rating Scales, Adolescents, Depression (Psychology)
Salomonsen-Sautel, Stacy; Sakai, Joseph T.; Thurstone, Christian; Corley, Robin; Hopfer, Christian – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To assess the prevalence and frequency of medical marijuana diversion and use among adolescents in substance abuse treatment and to identify factors related to their medical marijuana use. Method: This study calculated the prevalence and frequency of diverted medical marijuana use among adolescents (n = 164), ages 14-18 years (mean age…
Descriptors: Substance Abuse, Marijuana, Incidence, Adolescents
Paloyelis, Yannis; Mehta, Mitul A.; Faraone, Stephen V.; Asherson, Philip; Kuntsi, Jonna – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Attention-deficit/hyperactivity disorder (ADHD) has been linked to deficits in the dopaminergic reward-processing circuitry; yet, existing evidence is limited, and the influence of genetic variation affecting dopamine signaling remains unknown. We investigated striatal responsivity to rewards in ADHD combined type (ADHD-CT) using…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Cues, Adolescents
Galanter, Cathryn A.; Hundt, Stephanie R.; Goyal, Parag; Le, Jenna; Fisher, Prudence W. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: The "DSM-IV-TR "criteria for a manic episode and bipolar disorder (BD) were developed for adults but are used for children. The manner in which clinicians and researchers interpret these criteria may have contributed to the increase in BD diagnoses given to youth. Research interviews are designed to improve diagnostic reliability and…
Descriptors: Criteria, Psychiatry, Adolescents, Scoring
Gadow, Kenneth D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: This study compared the differential severity of specific symptoms of schizophrenia spectrum disorder (SSD) in children with autism spectrum disorder (ASD) and child psychiatry outpatient referrals (controls). Each group was further subdivided into subgroups with and without co-occurring attention-deficit/hyperactivity disorder (ADHD).…
Descriptors: Rating Scales, Attention Deficit Hyperactivity Disorder, Autism, Etiology
Max, Jeffrey E.; Wilde, Elisabeth A.; Bigler, Erin D.; Thompson, Wesley K.; MacLeod, Marianne; Vasquez, Ana C.; Merkley, Tricia L.; Hunter, Jill V.; Chu, Zili D.; Yallampalli, Ragini; Hotz, Gillian; Chapman, Sandra B.; Yang, Tony T.; Levin, Harvey S. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To study magnetic resonance imaging (MRI) correlates of novel (new-onset) psychiatric disorders (NPD) after traumatic brain injury (TBI) and orthopedic injury (OI). Method: Participants were 7 to 17 years of age at the time of hospitalization for either TBI or OI. The study used a prospective, longitudinal, controlled design with…
Descriptors: Outcome Measures, Brain, Diagnostic Tests, Head Injuries
Tiemeier, Henning; Velders, Fleur P.; Szekely, Eszter; Roza, Sabine J.; Dieleman, Gwen; Jaddoe, Vincent W. V.; Uitterlinden, Andre G.; White, Tonya J. H.; Bakermans-Kranenburg, Marian J.; Hofman, Albert; Van IJzendoorn, Marinus H.; Hudziak, James J.; Verhulst, Frank C. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: First, we give an overview of child psychiatric research in the Generation R Study, a population-based cohort from fetal life forward. Second, we examine within Generation R whether the functional polymorphism (5-HTTLPR) in the promoter of the serotonin transporter gene interacts with prenatal maternal chronic difficulties, prenatal…
Descriptors: Pregnancy, Emotional Development, Anxiety, Emotional Problems
Vidair, Hilary B.; Reyes, Jazmin A.; Shen, Sa; Parrilla-Escobar, Maria A.; Heleniak, Charlotte M.; Hollin, Ilene L.; Woodruff, Scott; Turner, J. Blake; Rynn, Moira A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: Children of depressed and/or anxious parents are at increased risk for developing psychiatric disorders. Little research has focused on screening parents bringing their children for psychiatric evaluation, and few studies have included fathers or Hispanic children. This study had the following aims: 1) to identify current symptom rates…
Descriptors: Attention Deficit Hyperactivity Disorder, Mothers, Mental Health Programs, Psychopathology
Reyes, Magdalena M.; Panza, Kaitlyn E.; Martin, Andres; Bloch, Michael H. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: To determine whether there is evidence of a time-lag bias in the publication of pediatric antidepressant trials. Method: We conducted a meta-analysis of published and unpublished randomized placebo-controlled trials of serotonin reuptake inhibitors (SRIs) in subjects less than 18 years of age with major depressive disorder. Our main…
Descriptors: Evidence, Psychiatry, Depression (Psychology), Pediatrics
Hoffman, Ellen J.; State, Matthew W. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: This review considers the impact of chromosomal studies on the understanding of childhood neuropsychiatric syndromes, highlighting key discoveries, advances in technology, and new challenges faced by clinicians trying to interpret recent findings. Method: We review the literature on the genetics of child psychiatric disorders, including…
Descriptors: Attention Deficit Hyperactivity Disorder, Investigations, Schizophrenia, Emotional Disturbances
Bagot, Rosemary C.; Meaney, Michael J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Child and adolescent psychiatry is rife with examples of the sustained effects of early experience on brain function. The study of behavioral genetics provides evidence for a relation between genomic variation and personality and with the risk for psychopathology. A pressing challenge is that of "conceptually" integrating findings from…
Descriptors: Psychiatry, Psychopathology, Personality, Genetics
Haworth, Claire M. A.; Plomin, Robert – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To consider recent findings from quantitative genetic research in the context of molecular genetic research, especially genome-wide association studies. We focus on findings that go beyond merely estimating heritability. We use learning abilities and disabilities as examples. Method: Recent twin research in the area of learning…
Descriptors: Learning Problems, Disabilities, Psychiatry, Genetics
Pine, Daniel S.; Ernst, Monique; Leibenluft, Ellen – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To place imaging-genetics research in the context of child psychiatry. Method: A conceptual overview is provided, followed by discussion of specific research examples. Results: Imaging-genetics research is described linking brain function to two specific genes, for the serotonin-reuptake-transporter protein and a monoamine oxidase…
Descriptors: Psychiatry, Genetics, Brain, Drug Therapy
