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Showing 1 to 15 of 116 results
Beyond Autism: A Baby Siblings Research Consortium Study of High-Risk Children at Three Years of Age
Peer reviewed
Direct linkMessinger, Daniel; Young, Gregory S.; Ozonoff, Sally; Dobkins, Karen; Carter, Alice; Zwaigenbaum, Lonnie; Landa, Rebecca J.; Charman, Tony; Stone, Wendy L.; Constantino, John N.; Hutman, Ted; Carver, Leslie J.; Bryson, Susan; Iverson, Jana M.; Strauss, Mark S.; Rogers, Sally J.; Sigman, Marian – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: First-degree relatives of persons with an autism spectrum disorder (ASD) are at increased risk for ASD-related characteristics. As little is known about the early expression of these characteristics, this study characterizes the non-ASD outcomes of 3-year-old high-risk (HR) siblings of children with ASD. Method: Two groups of children…
Descriptors: Outcome Measures, Autism, Early Intervention, Siblings
Rogers, Cynthia E.; Lenze, Shannon N.; Luby, Joan L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: Preterm children are at greater risk for psychiatric disorders, including anxiety disorders and attention-deficit/hyperactivity disorder (ADHD), than their term-born peers. Prior research has focused primarily on children born at early gestational ages. Less is known about the rate of psychiatric disorders among late preterm or early…
Descriptors: Parent Influence, Anxiety Disorders, Depression (Psychology), Preschool Children
Towbin, Kenneth; Axelson, David; Leibenluft, Ellen; Birmaher, Boris – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: Bipolar disorder--not otherwise specified (BP-NOS) and severe mood dysregulation (SMD) are severe mood disorders that were defined to address questions about the diagnosis of bipolar disorder (BD) in youth. SMD and BP-NOS are distinct phenotypes that differ in clinical presentation and longitudinal course. The purpose of this review is…
Descriptors: Psychological Patterns, Mental Disorders, Genetics, Symptoms (Individual Disorders)
Miklowitz, David J.; Schneck, Christopher D.; Singh, Manpreet K.; Taylor, Dawn O.; George, Elizabeth L.; Cosgrove, Victoria E.; Howe, Meghan E.; Dickinson, L. Miriam; Garber, Judy; Chang, Kiki D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: Depression and brief periods of (hypo)mania are linked to an increased risk of progression to bipolar I or II disorder (BD) in children of bipolar parents. This randomized trial examined the effects of a 4-month family-focused therapy (FFT) program on the 1-year course of mood symptoms in youth at high familial risk for BD, and explored…
Descriptors: Rating Scales, Therapy, Depression (Psychology), Early Intervention
Richardson, Gale A.; Larkby, Cynthia; Goldschmidt, Lidush; Day, Nancy L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: To investigate the direct effects of prenatal cocaine exposure (PCE) on adolescent drug use, while controlling for other predictors of adolescent use. Method: Data are from a longitudinal study of PCE in which women and their offspring were assessed throughout childhood. Adolescents were interviewed at 15 years about their age at…
Descriptors: Violence, Child Abuse, Prenatal Influences, Drug Abuse
Singh, Manpreet K.; Chang, Kiki D.; Kelley, Ryan G.; Cui, Xu; Sherdell, Lindsey; Howe, Meghan E.; Gotlib, Ian H.; Reiss, Allan L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: Bipolar disorder (BD) is a debilitating psychiatric condition that commonly begins in adolescence, a developmental period that has been associated with increased reward seeking. Because youth with BD are especially vulnerable to negative risk-taking behaviors, understanding the neural mechanisms by which dysregulated affect interacts…
Descriptors: Adolescents, Priming, Rewards, Depression (Psychology)
Olfson, Mark; Huang, Cecilia; Gerhard, Tobias; Winterstein, Almut G.; Crystal, Stephen; Allison, Paul D.; Marcus, Steven C. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: This study examined associations between stimulant use and risk of cardiovascular events and symptoms in youth with attention-deficit/hyperactivity disorder and compared the risks associated with methylphenidate and amphetamines. Method: Claims were reviewed of privately insured young people 6 to 21 years old without known…
Descriptors: Attention Deficit Hyperactivity Disorder, Stimulants, Cohort Analysis, Risk
Kumra, Sanjiv; Robinson, Paul; Tambyraja, Rabindra; Jensen, Daniel; Schimunek, Caroline; Houri, Alaa; Reis, Tiffany; Lim, Kelvin – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: In early-onset schizophrenia (EOS), the earliest structural brain volumetric abnormalities appear in the parietal cortices. Early exposure to cannabis may represent an environmental risk factor for developing schizophrenia. This study characterized cerebral cortical gray matter structure in adolescents in regions of interest (ROIs) that…
Descriptors: Marijuana, Schizophrenia, Brain, At Risk Persons
Rogers, Cynthia E.; Anderson, Peter J.; Thompson, Deanne K.; Kidokoro, Hiroyuki; Wallendorf, Michael; Treyvaud, Karli; Roberts, Gehan; Doyle, Lex W.; Neil, Jeffrey J.; Inder, Terrie E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Preterm children are at risk for social-emotional difficulties, including autism and attention-deficit/hyperactivity disorder. We assessed the relationship of regional brain development in preterm children, evaluated via magnetic resonance imaging (MRI) at term-equivalent postmenstrual age (TEA), to later social-emotional difficulties.…
Descriptors: Attention Deficit Hyperactivity Disorder, Emotional Problems, Body Weight, Pregnancy
Glatt, Stephen J.; Tsuang, Ming T.; Winn, Mary; Chandler, Sharon D.; Collins, Melanie; Lopez, Linda; Weinfeld, Melanie; Carter, Cindy; Schork, Nicholas; Pierce, Karen; Courchesne, Eric – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Autism spectrum disorders (ASDs) are highly heritable neurodevelopmental disorders that onset clinically during the first years of life. ASD risk biomarkers expressed early in life could significantly impact diagnosis and treatment, but no transcriptome-wide biomarker classifiers derived from fresh blood samples from children with…
Descriptors: Delayed Speech, Autism, Toddlers, Infants
Tiemeier, Henning; Velders, Fleur P.; Szekely, Eszter; Roza, Sabine J.; Dieleman, Gwen; Jaddoe, Vincent W. V.; Uitterlinden, Andre G.; White, Tonya J. H.; Bakermans-Kranenburg, Marian J.; Hofman, Albert; Van IJzendoorn, Marinus H.; Hudziak, James J.; Verhulst, Frank C. – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: First, we give an overview of child psychiatric research in the Generation R Study, a population-based cohort from fetal life forward. Second, we examine within Generation R whether the functional polymorphism (5-HTTLPR) in the promoter of the serotonin transporter gene interacts with prenatal maternal chronic difficulties, prenatal…
Descriptors: Pregnancy, Emotional Development, Anxiety, Emotional Problems
Hammerness, Paul G.; Perrin, James M.; Shelley-Abrahamson, Rachel; Wilens, Timothy E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: This review provides an update on the cardiovascular impact of therapeutic stimulant-class medication for children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Method: Relevant clinical literature was ascertained using PubMed searches limited to human studies and the English language as of May 2011. Current…
Descriptors: Attention Deficit Hyperactivity Disorder, Metabolism, Stimulants, Adolescents
Axelson, David A.; Birmaher, Boris; Strober, Michael A.; Goldstein, Benjamin I.; Ha, Wonho; Gill, Mary Kay; Goldstein, Tina R.; Yen, Shirley; Hower, Heather; Hunt, Jeffrey I.; Liao, Fangzi; Iyengar, Satish; Dickstein, Daniel; Kim, Eunice; Ryan, Neal D.; Frankel, Erica; Keller, Martin B. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: To determine the rate of diagnostic conversion from an operationalized diagnosis of bipolar disorder not otherwise specified (BP-NOS) to bipolar I disorder (BP-I) or bipolar II disorder (BP-II) in youth over prospective follow-up and to identify factors associated with conversion. Method: Subjects were 140 children and adolescents…
Descriptors: Intervals, At Risk Persons, Adolescents, Mental Disorders
Hudson, Jennifer L.; Dodd, Helen F.; Lyneham, Heidi J.; Bovopoulous, Nataly – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: Behavioral inhibition (BI) in early childhood is associated with increased risk for anxiety. The present research examines BI alongside family environment factors, specifically maternal negativity and overinvolvement, maternal anxiety, and mother-child attachment, with a view to providing a broader understanding of the development of…
Descriptors: Anxiety Disorders, Child Rearing, Inhibition, Path Analysis
Groen-Blokhuis, Maria M.; Middeldorp, Christel M.; van Beijsterveldt, Catharina E. M.; Boomsma, Dorret I. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: Low birth weight (LBW) is associated with attention problems (AP) and attention-deficit/hyperactivity disorder (ADHD). The etiology of this association is unclear. We investigate whether there is a causal influence of birth weight (BW) on AP and whether the BW effect is mediated by catch-up growth (CUG) in low-BW children. Method:…
Descriptors: Attention Deficit Hyperactivity Disorder, Twins, Body Weight, Etiology
