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50 Years of ERIC
50 Years of ERIC
The Education Resources Information Center (ERIC) is celebrating its 50th Birthday! First opened on May 15th, 1964 ERIC continues the long tradition of ongoing innovation and enhancement.

Learn more about the history of ERIC here. PDF icon

Showing 1 to 15 of 16 results
A Controlled Trial of Extended-Release Guanfacine and Psychostimulants for Attention-Deficit/Hyperactivity Disorder
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Wilens, Timothy E.; Bukstein, Oscar; Brams, Matthew; Cutler, Andrew J.; Childress, Ann; Rugino, Thomas; Lyne, Andrew; Grannis, Kara; Youcha, Sharon – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: To examine efficacy, tolerability, and safety of guanfacine extended release (GXR; less than or equal to 4 mg/d) adjunctive to a long-acting psychostimulant for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents 6 to 17 years of age with suboptimal, but partial, response to psychostimulant…
Descriptors: Attention Deficit Hyperactivity Disorder, Safety, Rating Scales, Severity (of Disability)
Cardiovascular Risk of Stimulant Treatment in Pediatric Attention-Deficit/Hyperactivity Disorder: Update and Clinical Recommendations
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Hammerness, Paul G.; Perrin, James M.; Shelley-Abrahamson, Rachel; Wilens, Timothy E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: This review provides an update on the cardiovascular impact of therapeutic stimulant-class medication for children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Method: Relevant clinical literature was ascertained using PubMed searches limited to human studies and the English language as of May 2011. Current…
Descriptors: Attention Deficit Hyperactivity Disorder, Metabolism, Stimulants, Adolescents
Genome-Wide Association Study of the Child Behavior Checklist Dysregulation Profile
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Mick, Eric; McGough, James; Loo, Sandra; Doyle, Alysa E.; Wozniak, Janet; Wilens, Timothy E.; Smalley, Susan; McCracken, James; Biederman, Joseph; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: A potentially useful tool for understanding the distribution and determinants of emotional dysregulation in children is a Child Behavior Checklist profile, comprising the Attention Problems, Anxious/Depressed, and Aggressive Behavior clinical subscales (CBCL-DP). The CBCL-DP indexes a heritable trait that increases susceptibility for…
Descriptors: Attention Deficit Hyperactivity Disorder, Check Lists, Aggression, Psychopathology
Does ADHD Predict Substance-Use Disorders? A 10-Year Follow-up Study of Young Adults with ADHD
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Wilens, Timothy E.; Martelon, MaryKate; Joshi, Gagan; Bateman, Clancey; Fried, Ronna; Petty, Carter; Biederman, Joseph – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: High rates of substance-use disorders (SUD) have been found in samples of adolescents and adults with attention-deficit/hyperactivity disorder (ADHD). Predictors of SUD in children with ADHD who are at risk for the development of SUDs remain understudied. The main aims of this study were to identify clinically meaningful characteristics…
Descriptors: Attention Deficit Hyperactivity Disorder, Smoking, Psychopathology, At Risk Persons
Do Executive Function Deficits Predict Later Substance Use Disorders among Adolescents and Young Adults?
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Wilens, Timothy E.; Martelon, MaryKate; Fried, Ronna; Petty, Carter; Bateman, Clancey; Biederman, Joseph – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: There is increasing interest regarding the risk and overlap of executive function deficits (EFDs) in stable cigarette smoking and substance use disorders (SUD). Therefore, we examined whether earlier EFD was a risk factor for subsequent cigarette smoking and SUD and further explored the relationship between EFD and SUD. Method: We…
Descriptors: Attention Deficit Hyperactivity Disorder, Smoking, Psychopathology, At Risk Persons
Safety and Efficacy of ABT-089 in Pediatric Attention-Deficit/Hyperactivity Disorder: Results from Two Randomized Placebo-Controlled Clinical Trials
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Wilens, Timothy E.; Gault, Laura M.; Childress, Ann; Kratochvil, Christopher J.; Bensman, Lindsey; Hall, Coleen M.; Olson, Evelyn; Robieson, Weining Z.; Garimella, Tushar S.; Abi-Saab, Walid M.; Apostol, George; Saltarelli, Mario D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: To assess the safety and efficacy of ABT-089, a novel alpha[subscript 4]beta[subscript 2] neuronal nicotinic receptor partial agonist, vs. placebo in children with attention-deficit/hyperactivity disorder (ADHD). Method: Two multicenter, randomized, double-blind, placebo-controlled, parallel-group studies of children 6 through 12 years…
Descriptors: Attention Deficit Hyperactivity Disorder, Physical Examinations, Safety, Rating Scales
Family-Based Genome-Wide Association Scan of Attention-Deficit/Hyperactivity Disorder
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Mick, Eric; Todorov, Alexandre; Smalley, Susan; Hu, Xiaolan; Loo, Sandra; Todd, Richard D.; Biederman, Joseph; Byrne, Deirdre; Dechairo, Bryan; Guiney, Allan; McCracken, James; McGough, James; Nelson, Stanley F.; Reiersen, Angela M.; Wilens, Timothy E.; Wozniak, Janet; Neale, Benjamin M.; Faraone, Stephen V. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Genes likely play a substantial role in the etiology of attention-deficit/hyperactivity disorder (ADHD). However, the genetic architecture of the disorder is unknown, and prior genome-wide association studies (GWAS) have not identified a genome-wide significant association. We have conducted a third, independent, multisite GWAS of…
Descriptors: Evidence, Attention Deficit Hyperactivity Disorder, Quality Control, Genetics
A Double-Blind, Randomized, Placebo-Controlled Trial of Divalproex Extended-Release in the Treatment of Bipolar Disorder in Children and Adolescents
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Wagner, Karen Dineen; Redden, Laura; Kowatch, Robert A.; Wilens, Timothy E.; Segal, Scott; Chang, Kiki; Wozniak, Patricia; Vigna, Namita V.; Abi-Saab, Walid; Saltarelli, Mario – Journal of the American Academy of Child & Adolescent Psychiatry, 2009
A double-blind study that involves 150 patients aged 10-17 on the effect of divalproex extended-release in the treatment of bipolar disorder shows that the drug was similar to placebo based on adverse events and that no treatment effect was observed in the drug. The drug is not suitable for treatment of youths with bipolar I disorder, mixed or…
Descriptors: Patients, Drug Therapy, Depression (Psychology), Children
Misuse and Diversion of Stimulants Prescribed for ADHD: A Systematic Review of the Literature
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Wilens, Timothy E.; Adler, Lenard A.; Adams, Jill; Sgambati, Stephanie; Rotrosen, John; Sawtelle, Robert; Utzinger, Linsey; Fusillo, Steven – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
The article examines various studies of ADHD and finds that individuals both with and without ADHD misuse stimulant medications, therefore suggesting careful monitoring of high-risk individuals.
Descriptors: Attention Deficit Disorders, Hyperactivity, Drug Abuse, Drug Therapy
Varying the Wear Time of the Methylphenidate Transdermal System in Children with Attention-Deficit/Hyperactivity Disorder
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Wilens, Timothy E.; Boellner, Samuel W.; Lopez, Frank A.; Turnbow, John M.; Wigal, Sharon B.; Childress, Ann C.; Abikoff, Howard B.; Manos, Michael J. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study investigated the impact of variable wear times of the methylphenidate transdermal system in children with attention-deficit/hyperactivity disorder (ADHD). It was concluded that duration of medication effect was directly related to the wear time of the methylphenidate transdermal system patch.
Descriptors: Hyperactivity, Attention Deficit Disorders, Children, Drug Therapy
Effects of Long-Term Atomoxetine Treatment for Young Children with Attention-Deficit/Hyperactivity Disorder
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Kratochvil, Christopher J.; Wilens, Timothy E.; Greenhill, Laurence L.; Gao, Haitao; Baker, Kurt D.; Feldman, Peter D.; Gelowitz, Douglas L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2006
Objective: The purpose of this 13-study (seven double-blind/placebo-controlled, six open-label) meta-analysis is to determine the effectiveness and tolerability of long-term atomoxetine treatment among young children with attention-deficit/hyperactivity disorder (ADHD). Method: Data were pooled from 6- and 7-year-olds (N = 272) who met DSM-IV…
Descriptors: Attention Deficit Hyperactivity Disorder, Young Children, Rating Scales, Trend Analysis
Do Children and Adolescents with ADHD Respond Differently to Atomoxetine?
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Wilens, Timothy E.; Kratochvil, Christopher; Newcorn, Jeffrey H.; Gao, Haitao – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: Controversy exists over changes in tolerability and response to medications across the life span. Here the authors report data contrasting the efficacy and tolerability of atomoxetine between children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Method: Data were analyzed for children ages 6-11 (510 atomoxetine,…
Descriptors: Adolescents, Rating Scales, Hyperactivity, Attention Deficit Disorders
Characteristics of Adolescents and Young Adults with ADHD Who Divert or Misuse Their Prescribed Medications
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Wilens, Timothy E.; Gignac, Martin; Swezey, Allison; Monuteaux, Michael C.; Biederman, Joseph – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: Little is known about the risks and characteristics of attention-deficit/hyperactivity disorder (ADHD) patients who misuse or divert their stimulant medications. As part of a 10-year longitudinal study of youths with ADHD, the authors evaluated medication diversion or misuse at the last follow-up period. Method: Structured psychiatric…
Descriptors: Patients, Adolescents, Young Adults, Siblings
Pharmacological Management of a Youth with ADHD, Marijuana Use, and Mood Symptoms
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Kratochvil, Christopher J.; Wilens, Timothy E.; Upadhyaya, Himanshu – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
This article deals with a 16-year-old boy who is referred by his parents to address his academic decline and mood symptoms. He was diagnosed with attention-deficit/hyperactivity disorder (ADHD) 7 years ago, but his parents had opted not to have it treated. The patient has prominent inattention and distractibility, with complaints of internal…
Descriptors: Psychological Patterns, Marijuana, Hyperactivity, Attention Deficit Disorders
Treatment of ADHD with Stimulant Medications: Response to Nissen Perspective in the New England Journal of Medicine
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Biederman, Joseph; Spencer, Thomas J.; Wilens, Timothy E.; Prince, Jefferson B.; Faraone, Stephen V. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
This article is a response to Dr. Steven E. Nissen's comments (Nissen, 2006) about attention deficit/hyperactivity disorder (ADHD) and its treatment with stimulant medications. In this article, the authors refute his arguments and provide accurate information. Here, they answer the questions, such as: (1) Do stimulants increase the risk for sudden…
Descriptors: Stimulants, Hyperactivity, Attention Deficit Disorders, Risk
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