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50 Years of ERIC
50 Years of ERIC
The Education Resources Information Center (ERIC) is celebrating its 50th Birthday! First opened on May 15th, 1964 ERIC continues the long tradition of ongoing innovation and enhancement.

Learn more about the history of ERIC here. PDF icon

Showing all 15 results
Treatment Moderators and Predictors of Outcome in the Treatment of Early Age Mania (TEAM) Study
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Vitiello, Benedetto; Riddle, Mark A.; Yenokyan, Gayane; Axelson, David A.; Wagner, Karen D.; Joshi, Paramjit; Walkup, John T.; Luby, Joan; Birmaher, Boris; Ryan, Neal D.; Emslie, Graham; Robb, Adelaide; Tillman, Rebecca – Journal of the American Academy of Child & Adolescent Psychiatry, 2012
Objective: Both the diagnosis and treatment of bipolar disorder in youth remain the subject of debate. In the Treatment of Early Age Mania (TEAM) study, risperidone was more effective than lithium or divalproex in children diagnosed with bipolar mania and highly comorbid with attention-deficit/hyperactivity disorder (ADHD). We searched for…
Descriptors: Attention Deficit Hyperactivity Disorder, Obesity, Schizophrenia, Symptoms (Individual Disorders)
Course of Subthreshold Bipolar Disorder in Youth: Diagnostic Progression from Bipolar Disorder Not Otherwise Specified
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Axelson, David A.; Birmaher, Boris; Strober, Michael A.; Goldstein, Benjamin I.; Ha, Wonho; Gill, Mary Kay; Goldstein, Tina R.; Yen, Shirley; Hower, Heather; Hunt, Jeffrey I.; Liao, Fangzi; Iyengar, Satish; Dickstein, Daniel; Kim, Eunice; Ryan, Neal D.; Frankel, Erica; Keller, Martin B. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: To determine the rate of diagnostic conversion from an operationalized diagnosis of bipolar disorder not otherwise specified (BP-NOS) to bipolar I disorder (BP-I) or bipolar II disorder (BP-II) in youth over prospective follow-up and to identify factors associated with conversion. Method: Subjects were 140 children and adolescents…
Descriptors: Intervals, At Risk Persons, Adolescents, Mental Disorders
Differential Patterns of Abnormal Activity and Connectivity in the Amygdala-Prefrontal Circuitry in Bipolar-I and Bipolar-NOS Youth
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Ladouceur, Cecile D.; Farchione, Tiffany; Diwadkar, Vaibhav; Pruitt, Patrick; Radwan, Jacqueline; Axelson, David A.; Birmaher, Boris; Phillips, Mary L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: The functioning of neural systems supporting emotion processing and regulation in youth with bipolar disorder not otherwise specified (BP-NOS) remains poorly understood. We sought to examine patterns of activity and connectivity in youth with BP-NOS relative to youth with bipolar disorder type I (BP-I) and healthy controls (HC). Method:…
Descriptors: Brain, Brain Hemisphere Functions, Mental Disorders, Emotional Response
Sleep Items in the Child Behavior Checklist: A Comparison with Sleep Diaries, Actigraphy, and Polysomnography
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Gregory, Alice M.; Cousins, Jennifer C.; Forbes, Erika E.; Trubnick, Laura; Ryan, Neal D.; Axelson, David A.; Birmaher, Boris; Sadeh, Avi; Dahl, Ronald E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2011
Objective: The Child Behavior Checklist is sometimes used to assess sleep disturbance despite not having been validated for this purpose. This study examined associations between the Child Behavior Checklist sleep items and other measures of sleep. Method: Participants were 122 youth (61% female, aged 7 through 17 years) with anxiety disorders…
Descriptors: Anxiety Disorders, Check Lists, Sleep, Child Behavior
Altered Development of White Matter in Youth at High Familial Risk for Bipolar Disorder: A Diffusion Tensor Imaging Study
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Versace, Amelia; Ladouceur, Cecile D.; Romero, Soledad; Birmaher, Boris; Axelson, David A.; Kupfer, David J.; Phillips, Mary L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: To study white matter (WM) development in youth at high familial risk for bipolar disorder (BD). WM alterations are reported in youth and adults with BD. WM undergoes important maturational changes in adolescence. Age-related changes in WM microstructure using diffusion tensor imaging with tract-based spatial statistics in healthy…
Descriptors: Symptoms (Individual Disorders), Brain Hemisphere Functions, Risk, Genetics
Clinical, Demographic, and Familial Correlates of Bipolar Spectrum Disorders among Offspring of Parents with Bipolar Disorder
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Goldstein, Benjamin I.; Shamseddeen, Wael; Axelson, David A.; Kalas, Cathy; Monk, Kelly; Brent, David A.; Kupfer, David J.; Birmaher, Boris – Journal of the American Academy of Child & Adolescent Psychiatry, 2010
Objective: Despite increased risk, most offspring of parents with bipolar disorder (BP) do not manifest BP. The identification of risk factors for BP among offspring could improve preventive and treatment strategies. We examined this topic in the Pittsburgh Bipolar Offspring Study (BIOS). Method: Subjects included 388 offspring, ages 7-17 years,…
Descriptors: Mental Disorders, Risk, Children, Adolescents
Objective Sleep in Pediatric Anxiety Disorders and Major Depressive Disorder
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Forbes, Erika E.; Bertocci, Michele A.; Gregory, Alice M.; Ryan, Neal D.; Axelson, David A.; Birmaher, Boris; Dahl, Ronald E. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to examine sleep problems encountered in anxiety and depressive disorders among children and adolescents is conducted. Results indicated subjective and objective sleep problems in children and adolescents with anxiety disorders and need to be kept in mind when treating young anxious people.
Descriptors: Sleep, Adolescents, Children, Anxiety
Subcortical Gray Matter Volume Abnormalities in Healthy Bipolar Offspring: Potential Neuroanatomical Risk Marker for Bipolar Disorder?
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Ladouceur, Cecile D.; Almeida, Jorge R. C.; Birmaher, Boris; Axelson, David A.; Nau, Sharon; Kalas, Catherine; Monk, Kelly; Kupfer, David J.; Phillips, Mary L. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study is conducted to examine the extent to which bipolar disorder (BD) is associated with gray matter volume abnormalities in brain regions in healthy bipolar offspring relative to age-matched controls. Results show increased gray matter volume in the parahippocampus/hippocampus in healthy offspring at genetic risk for BD.
Descriptors: Language Impairments, Neurology, Brain, Mental Disorders
Mother-Child Interactions in Depressed Children and Children at High Risk and Low Risk for Future Depression
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Dietz, Laura J.; Birmaher, Boris; Williamson, Douglas E.; Silk, Jennifer S.; Dahl, Ronald E.; Axelson, David A.; Ehmann, Mary; Ryan, Neal D. – Journal of the American Academy of Child & Adolescent Psychiatry, 2008
A study to investigate the differences in mother and child interactions of depressed children and adolescents, nondepressed high-risk youths, and healthy controls was conducted. Results revealed increased family discord with depressed children whereas intermediate levels of control and disengagement were seen in families with high-risk children.
Descriptors: Mothers, Depression (Psychology), Parent Child Relationship, Adolescents
Dialectical Behavior Therapy for Adolescents with Bipolar Disorder: A 1-Year Open Trial
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Goldstein, Tina R.; Axelson, David A.; Birmaher, Boris; Brent, David A. – Journal of the American Academy of Child & Adolescent Psychiatry, 2007
Objective: To describe an adapted version of dialectical behavior therapy for adolescents with bipolar disorder. Method: The dialectical behavior therapy intervention is delivered over 1 year and consists of two modalities: family skills training (conducted with individual family units) and individual therapy. The acute treatment period (6 months)…
Descriptors: Intervention, Self Destructive Behavior, Behavior Modification, Adolescents
Steady-State Clinical Pharmacokinetics of Bupropion Extended-Release In Youths
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Daviss, W. Burleson; Perel, James M.; Birmaher, Boris; Rudolph, George R.; Melhem, Imad; Axelson, David A.; Brent, David A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2006
Objective: To examine in children and adolescents the 24-hour, steady-state clinical pharmacokinetics of an extended-release (XL) formulation of bupropion (Wellbutrin XL). Method: Subjects were six male and four female patients (ages 11.5-16.2 years) prescribed bupropion XL in morning daily doses of either 150 mg (n = 5) or 300 mg (n = 5) for at…
Descriptors: Pharmacology, Patients, Children, Adolescents
Steady-State Pharmacokinetics of Bupropion SR in Juvenile Patients
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Daviss, W. Burleson; Perel, James M.; Rudolph, George R.; Axelson, David A.; Gilchrist, Richard; Nuss, Sharon; Birmaher, Boris; Brent, David A. – Journal of the American Academy of Child and Adolescent Psychiatry, 2005
Objective: To examine the steady-state pharmacokinetic properties of bupropion sustained release (SR) and their potential developmental differences in youths. Method: Eleven boys and eight girls aged 11 to 17 years old were prescribed bupropion SR monotherapy for attention-deficit/hyperactivity disorder (n = 16) and/or depressive disorders (n =…
Descriptors: Psychiatry, Pharmacology, Patients, Hyperactivity
Clinical Presentation and Course of Depression in Youth: Does Onset in Childhood Differ from Onset in Adolescence?
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Birmaher, Boris; Williamson, Douglas E.; Dahl, Ronald E.; Axelson, David A.; Kaufman, Joan; Dorn, Lorah D.; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To simultaneously and prospectively compare the clinical presentation, course, and parental psychiatric history between children and adolescents with major depressive disorder. Method: A group of prepubertal children (n = 46) and postpubertal adolescents (n = 22) were assessed with structured interviews for psychopathology and parental…
Descriptors: Psychiatry, Psychopathology, Adolescents, Anxiety
First Episode of Depression in Children at Low and High Familial Risk for Depression
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Williamson, Douglas E.; Birmaher, Boris; Axelson, David A.; Ryan, Neal D.; Dahl, Ronald E. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To examine the development of first-onset major depressive disorder (MDD) in children at high and low familial risk for depression in a prospective study. Method: High-risk children (n = 76) who were free of any lifetime affective disorder and had at least one first-degree and one second-degree relative with a lifetime history of…
Descriptors: Psychiatry, Age, Schizophrenia, Mothers
Psychosocial Functioning in Youths at High Risk to Develop Major Depressive Disorder.
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Birmaher, Boris; Bridge, Jeffrey A.; Williamson, Douglas E.; Brent, David A.; Dahl, Ronald E.; Axelson, David A.; Dorn, Lorah D.; Ryan, Neal D. – Journal of the American Academy of Child and Adolescent Psychiatry, 2004
Objective: To compare the psychosocial functioning of children and adolescents at high risk of major depressive disorder with youths with acute major depressive disorder and healthy controls. Method: High-risk (n = 57), major depressive disorder (n = 71), and healthy control (n = 48) youths and their families were recruited from 1987 to 1996 and…
Descriptors: Psychiatry, Psychopathology, Longitudinal Studies, Depression (Psychology)