Despite the emphasis on technology and the rapid proliferation of assistive technology devices, little is known about the specific uses of assistive technology with persons who vary in disability type, severity, and age. The present study conducted a comprehensive review and a systematic analysis of published reports of assistive technology and skill acquisition of persons with disabilities. Uses of assistive technology, its benefits and obstacles, are reviewed. The results provide indications why technology is often abandoned. Implications for practitioners and researchers are discussed.