This case study explored perceptions of friendship of an adolescent with Asperger syndrome. Data were collected through semi-structured interviews, photographs taken by the adolescent, and quality of life and friendship measures. Data were analyzed using grounded theory principles and organized into three themes: (1) characteristics of a friend; (2) family involvement; and (3) enjoyment of friendships and desire to have them. The adolescent appeared to enjoy having friends, was interested in pursuing friendships, and had a basic understanding of many characteristics of friendships. He described negotiating his own and his friend's focused interests. Family members played important roles in the establishment and maintenance of the adolescent's friendships.