The article focuses on public health research projects which are being conducted at two Indian colleges; Candeska Cikana Community College in Fort Trotten, North Dakota and Turtle Mountain Community College in Belcourt, North Dakota. Candeska Community College was given a 6 year grant funded by the National Institutes of Diabetes, Digestive and Kidney Diseases and is using the grant money to develop a grade K-12 diabetes based science education curriculum for schools. Turtle Mountain Community College is host to the Idea Network of Biomedical Research Excellence and is performing genetic research on a medical condition of interest to the Indian community called preclampsia, which is also known as toxemia.