Since its founding in 1968, Dine College in Tsaile, Arizona, has centered the curriculum on Dine language, history, and philosophy. "Sa'ah Naaghai Bik'eh Hozhoon," the Dine traditional living system, places human life in harmony with the natural world and the universe, providing protection from the imperfections in life and development of well-being. When applied to education, the philosophy provides a balance between Navajo and Western education. That mission has allowed the college to thrive, bringing success to its students. In April, the college celebrated its 40th anniversary and hosted its comprehensive re-accreditation visit by the Higher Learning Commission of the North Central Association. Dine College was the first tribal college chartered by a tribe, launching a movement that has now grown to 37 institutions in the American Indian Higher Education Consortium and around the world. In 1976, the college became the first tribal college to receive a two-year accreditation from the same regional accreditation agency that judges all other colleges and universities in the north central region of the country. In April 2002, the Higher Learning Commission granted Dine College eight years of accreditation. In this article, Dine College leaders discuss celebrations, challenges, and the college's essential mission.