There are clear health conditions that disproportionately affect the Hispanic population. One hundred twenty-four (45%) Hispanic and 153 (55%) White college students completed a questionnaire on cardiovascular disease (CVD) awareness, knowledge, and perceptions of risk. Results indicated that Hispanic students rated themselves as poorer in health, more overweight, poorer in nutrition, and less knowledgeable about CVD risk than did White students. Practitioners would benefit from developing CVD prevention programs that targeted the Hispanic population.