One of the aims of Educational Guidance is social development and learning in Secondary Education students who are in multicultural contexts. An increase in socio-emotional competencies is promoted through Guidance program interventions. The "Guidance Program for Socio-emotional Competencies" (in Spanish, "POCOSE") not only improves students' learning process and academic performance, it also favors their integration socially and at school, thus exercising a preventive function against future school failure and other risk factors, such as absenteeism, school drop-out, or violence (bullying). The broad cultural diversity which characterizes our Educational System requires identification of socioemotional competencies that are positively related to optimal learning and better socio-educational adjustment of secondary students who are in multicultural contexts, as well as identifying existing cultural differences in the process of teaching and learning these competencies. There is also a need for scientifically-validated programs for guidance and training in socio-emotional competencies, since these are an appropriate way to improve learning and socio-educational adjustment of Secondary Education students.