The National Institute of Alcohol Abuse and Alcoholism has called for the use of evidence-based approaches to address high-risk drinking prevalent on many college campuses. In line with this recommendation, the present study evaluated the efficacy of two evidence-based approaches to reducing alcohol use. One hundred and three college students in first-year experience courses were randomly assigned by class to participate in a computer-assisted online program (e-Chug Group), skills training program (Self-Management Group), or control condition (Exercise Group). The data indicate that heavier drinkers benefited from the e-Chug program, whereas lighter drinkers benefited from the self-management program. As such, colleges may yield more favorable results when forgoing a blanket approach to decreasing alcohol consumption in favor of matching students with an appropriate alcohol program. (Contains 2 tables, 2 footnotes and 1 figure.)