Isolation and identification of organic compounds is a necessary skill chemistry students must be able to do with proficiency. In this upper-level undergraduate laboratory, students isolate bisphenol-A (BPA; 4-4'-isopropylidenediphenol) from water using solid-phase extraction (SPE) followed by derivatization with analysis by GC-MS. The students learn the proper steps and techniques of SPE that include conditioning, equilibration, washing, and eluting. The students are then asked to identify the BPA peak from the GC-MS analysis of a mixture of standards based upon the molecular ion, keeping in mind the change in molecular weight upon derivatization. Interpretation of GC-MS data showed predictable fragmentation and highlights the formation of benzylic carbocations. Quantification was done by an external calibration curve and the sample was quantified and a percent recovery is calculated. (Contains 3 figures.)