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50 Years of ERIC
50 Years of ERIC
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Peer reviewed Peer reviewed
ERIC Number: EJ726107
Record Type: Journal
Publication Date: 2005-Jul-1
Pages: 6
Abstractor: Author
Reference Count: 0
ISBN: N/A
ISSN: ISSN-0021-9584
Generation, Isolation, and Characterization of a Stable Enol from Grignard Addition to a Bis-Ester: A Microscale Experiment for the Undergraduate Organic Chemistry Laboratory
Nicaise, Olivier J. C.; Ostrom, Kyle F.; Dalke, Brent J.
Journal of Chemical Education, v82 n7 p1059-1064 Jul 2005
An experiment is described that introduces students to the concept of temperature-dependent stability of the tetrahedral intermediate in an acyl-transfer reaction. The process involves the determination of the structure of an alpha-ketoester and its corresponding remarkably stable enol ester to suggest a mechanism for the formation of the products.
Descriptors: Organic Chemistry, Undergraduate Study, Higher Education, College Science, Science Experiments, Science Education, Thermodynamics
Journal of Chemical Education, Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Web site: http://jchemed.chem.wisc.edu/AboutJCE/contact.html.
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers: N/A