This article presents faculty perceptions of the first month of iPad deployment in a national college system and a case study describing the integration of mobile learning devices in one college, interpreted within the framework of a SWOT analysis. We include a brief history of the implementation; description of the three-tier structure of infrastructure, pedagogy, and content; faculty perceptions; and pedagogy interview findings. We collected data using 1) case study interviews, 2) a faculty dispositional survey, and 3) iPad lead faculty. Overall, the large-scale deployment of iPad mobile learning devices was associated with high faculty engagement in formal and informal professional development activities and adoption of an active student-centered pedagogy. In addition, the program stimulated innovative approaches to technical challenges; and it spurred development and evaluation of new digital content.