Background: Family cohesion may be a factor to prevent exposure of Hispanics in United States to secondhand smoke. Purpose: The purpose of this study was to evaluate one permutation of Mi Familia No Fuma (MFNF) and its resulting outputs or proximal client outcomes. Methods: MFNF is an approach to secondhand smoke prevention, using family cohesion through a family photo and one-year pledge. The intervention targets both smokers and non-smokers in the household. A cross-sectional survey was conducted after the intervention. Results: Of the 499 participants, 23% (N = 106) self-identified as smokers. Daily smokers reported an increase in willingness to create a smoke-free home. Family cohesion did not directly influence intent to create a smoke-free home or willingness to discuss the pledge with relatives. It was associated with increased belief that smoking in the home increases health risks and plans to place the photo/pledge in the home. Discussion: Levels of acculturation may affect individuals' willingness to enforce a smoke-free pledge in the home. Translation to Health Education Practice: Family cohesion is a relevant construct, particularly when included in a comprehensive and coordinated approach to reduce tobacco use within a Hispanic community. (Contains 3 tables and 3 figures.)