Students with Learning Disabilities (LD) often experience significant difficulty with academic content at the secondary level due to weaknesses in reading comprehension, written expression, math skills, and vocabulary learning skills. This article will highlight the usefulness of learning strategies for ensuring success of students with LD in the general education classroom, suggest unique approaches to modifying learning strategies, and emphasize the essential nature of generalization of learning strategies to impact student performance in the general curriculum. Included are general guidelines for modifying learning strategies including experimenting to see what works with students, individualizing strategies to reinforce student investment, and highlighting strategy components that produce results. (Contains 1 figure.)