This is the second in a series of articles about creating and sustaining systemic transformational change in school districts. The first article described the "AECT FutureMinds: Transforming America's School Systems" initiative for helping state education agencies (SEAs) facilitate paradigm change in their school districts. This article describes a methodology for creating and sustaining paradigm change that the FutureMinds initiative will use to help those SEAs transform school systems in their states. The methodology is called the "School System Transformation (SST) Protocol." Prior to describing the methodology, the authors describe the context for the design, development, and implementation of the methodology. (Contains 1 figure, 1 table and 1 footnote.)