In their review of the empirical research, Muis, Bendixen, and Haerle (2006) bring closure to the debate between domain specificity and domain generality of epistemic beliefs and provide a framework for future research. In response to their review, this article comments on issues that remain for those who wish to examine the nature of the interaction between epistemic domain specificity and domain generality and its relation to learning. These issues include methodological concerns, philosophical contributions, terminology, epistemology beyond academic domains, and educational implications.