As Mandarin gains popularity in the whole world, Mandarin education becomes valued by the countries all over the world. The United Nations classifies Mandarin as one of the six major languages, and the number of people who learn Mandarin in the whole world grows with each passing day as the mainland China market grows. This study discusses the learning effects of using multimedia assisted instruction on Mandarin vocabulary for Vietnamese students, taking into account the difficulty that Vietnamese students encountered during the learning process of multimedia assisted instruction. (Contains 5 figures and 2 tables.)