This study was conducted to investigate the disposition of students and parents towards the inclusion of sex education in the school curriculum in Cross River State. Using a random sampling technique, 602 secondary school students and 180 parents from Calabar, were selected for the study. Data were collected with the aid of self-administered questionnaire and analysed using descriptive statistical techniques. The majority of the students (90.70%) and parents (93.89%) were in support of the inclusion of sex education in the school curriculum. They believed that the teaching of sex education would compliment efforts being made towards the control of HIV/AIDS. Based on the results of the study, some recommendations were generated. (Contains 2 tables.)