The field of biotechnology, and specifically recombinant DNA technology, is transforming the way that many feel about the nature and purposes of biology. This newsletter annual supplement contains several articles addressing the topic of biotechnology and the importance that the topic should be given in science classes. James D. Watson's article, "Biotechnology: The Charge to Education," calling for teachers to foster DNA literacy in their classrooms, is the keynote of this document. Also included are: (1) "Searching for DNA Literacy" (Jeff Diamond); (2) "Biotechnology: A 'Scientific' Term in Name Only" (Henry I. Miller and Frank E. Young); (3) "The Science of Liposome-Based Pharmaceuticals"; (4) a list of 18 biotechnology related organizations; (5) a bibliography of 31 sources on biotechnology; (6) a list of 68 related journal articles; (7) a list of 12 related audiovisual materials; and (8) a review of a biotechnology instructional materials package called "Biostar." (CW)