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Direct linkBeckel-Mitchener, Andrea; Greenough, William T. – Mental Retardation and Developmental Disabilities Research Reviews, 2004
Fragile X syndrome (FXS) is characterized by a pattern of morphological, functional, and molecular characteristics with, in at least some cases, apparent relationships among phenotypic features at different levels. Gross morphology differences in the sizes of some human brain regions are accompanied by fine structural alterations in the shapes and…
Descriptors: Brain, Cognitive Processes, Molecular Structure, Genetic Disorders
Dong, Willie K.; Greenough, William T. – Mental Retardation and Developmental Disabilities Research Reviews, 2004
Neuronal and nonneuronal plasticity are both affected by environmental and experiential factors. Remodeling of existing neurons induced by such factors has been observed throughout the brain, and includes alterations in dendritic field dimensions, synaptogenesis, and synaptic morphology. The brain loci affected by these plastic neuronal changes…
Descriptors: Epilepsy, Mental Retardation, Autism, Brain
