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Gothelf, Doron; Schaer, Marie; Eliez, Stephan – Developmental Disabilities Research Reviews, 2008
Velo-cardio-facial syndrome (VCFS) has been in the focus of intensive research over the last 15 years. The syndrome represents a homogeneous model for studying the effect of a decreased dosage of genes on the development of brain structure and function and, consequently, on the emergence of schizophrenia-like psychotic disorder. In this review, we…
Descriptors: Schizophrenia, Risk, Neurology, Young Adults
Gothelf, Doron; Furfaro, Joyce A.; Penniman, Lauren C.; Glover, Gary H.; Reiss, Allan L. – Mental Retardation and Developmental Disabilities Research Reviews, 2005
Studying the biological mechanisms underlying mental retardation and developmental disabilities (MR/DD) is a very complex task. This is due to the wide heterogeneity of etiologies and pathways that lead to MR/DD. Breakthroughs in genetics and molecular biology and the development of sophisticated brain imaging techniques during the last decades…
Descriptors: Intelligence Quotient, Genetic Disorders, Mental Retardation, Developmental Disabilities

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